Hip disarticulation accounts for approximately 0.5% of the lower limb amputation. Wound management post-hip disarticulation is an arduous task. Honey has antioxidant, antibacterial and antiinflammatory properties. Antibacterial medical honey (Medihoney) usage is proven in wound care especially its role against antibioticresistant bacteria such as methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial medical honey in surgical wounds promotes faster healing, impedes tumour implantation and reduces amputation rate in diabetic wound. We report a case of an infected wound post-hip disarticulation in a 55-year-old Indian man that was treated successfully with antibacterial medical honey dressings.