Health professionals can be overwhelmed by the number of wound dressings currently available. Their choice is based on clinical evidence and also on their clinical expertise and experiences. Chitosan is a natural cationic polysaccharide that is the partially- to fully-deacetylated form of chitin. There is great interest in the use, as this biopolymer is the second most abundant after cellulose. Chitosan has been reported to have a number of useful properties in the management of wound healing. Here we share our experience regarding the management of five complex wounds treated with a novel Chitosan dressing. The outcomes of all cases were very encouraging, and the clinician feedback was positive.