In the management of chronic wounds, some of the important objectives include reduction of wound size and elimination of infection signs and pain management (Malaysian Ministry of Health [MOH], 2014). Most wound dressings are not able to support wound healing with a single product or therapy, hence, the introduction of a new formulation (Nair, 2017). To demonstrate its efficacy, nine patients were chosen which involved five cases of diabetic foot ulcer and four cases of venous leg ulcer. All wounds were cleaned and debrided where necessary, then a patented combination technology of SiO2 – + Ag+ + Chlorhexidine + Hyaluronic acid was applied as the primary dressing, with a non-adherent dressing as a secondary dressing. In cases where patients had exudating wounds, a pressure ulcer foam was added. The results of this case series demonstrated that it is possible for a single formulation to effectively support wound healing by reducing wound size and pain and eliminating infection signs.