This study investigates the effectiveness of hypochlorous acidoxidizing solution (AOS) in treating chronic wounds at the Wound Care Unit, Hospital Kuala Lumpur. The trial aims to assess healing speed, the reduction of infection rate, pain score, tissue improvement, and the control of inflammation. We chose six cases by simple random sampling and assessed them for 16 weeks. The cases include five cases of diabetic foot ulcer (DFU) and one case of abscess. The wounds were assessed for wound size and depth (in cm), visual analogue score (VAS), and wound bed preparation (WBP) score to evaluate the inflammation and the granulation tissue. We gave a score from 1 to 3 depending on the quantity of the exudation and from A to C depending on the quantity of granulation tissue. AOS shows a tremendous improvement in wound condition by augmenting wound healing, improvement in pain score, and reduction of infection. The small sample size of this study was its limitation; we need a larger sample to further assess the efficacy and full potential of AOS.