Managing chronic wounds is always a challenge in current healthcare, this study aims to assess the efficacy of combined super-oxidized therapy in treating chronic wounds. Ten patients were enrolled, and treatment efficacy was assessed by changes in wound size, pain score via Visual Analogue Scale and exudate level for period of 1 month. Statistical analysis was done using Wilcoxon Signed Ranks Test and paired T-Test. Patient satisfaction with treatment outcome was collected too. Overall there was significant reduction in wound size, pain and exudate level with good patient satisfaction on treatment outcome. No adverse events were reported.